Bittensor is an open-source protocol that powers a decentralized, blockchain-based machine learning network. Machine learning models train collaboratively and are rewarded in TAO based on the informational value they provide to the collective. TAO also provides external access, allowing users to extract information from the network while customizing its activities to their needs. The ultimate goal is to create a pure market for artificial intelligence, an incentivized environment in which buyers and sellers of this valuable commodity can interact in a trustless, open, and transparent way.

Centrifuge is a decentralized asset finance protocol that unlocks liquidity for real-world assets. Borrowers can finance their real-world assets without banks or other intermediaries, bridging them into Decentralized Finance (DeFi) to reduce the cost of capital for SMEs and provide DeFi investors with a stable source of yield that is uncorrelated from volatile crypto assets. Tinlake is Centrifuge's investment app, acting as an open marketplace of real-world asset pools. Investors can browse the pools provided by Asset Originators and invest in the ones that best suit them. Centrifuge Chain is the home for real-world assets (RWA) on the blockchain. It is a Proof-of-Stake blockchain built on Substrate that enables users to bring their assets on-chain as non-fungible tokens (NFTs).

Astar is a multi-chain smart contract platform that supports multiple blockchains and virtual machines. It connects the Polkadot ecosystem to Ethereum, Cosmos, and all major Layer 1 Blockchains.

Aleph Zero is a public blockchain with enhanced privacy based on an innovative, peer-reviewed Directed Acyclic Graph (DAG) and a Proof-of-Stake (PoS) consensus mechanism. It also incorporates the Substrate framework for interaction. This novel consensus has been developed with a privacy structure based on ZK-SNARKs cryptography and Secure Multi-Party Computation (sMPC). The protocol focuses on creating privacy-preserving distributed ledger technology (DLT) as an alternative to existing infrastructure barriers in sectors such as ESG, automotive, the Internet of Things (IoT), and healthcare.

Heima Network is a Layer 1 blockchain designed to achieve multi-chain and cross-chain interoperability. Heima is developed from the Litentry network and integrates core modules such as identity management, security, and privacy. Building on these foundations, Heima introduces an intent-based execution system, enabling frictionless cross-chain transactions across major ecosystems like Ethereum, Solana, and Polkadot.

Moonbeam is an Ethereum-compatible smart contract platform, providing an EVM implementation and Web3-compatible API. This Ethereum compatibility allows developers to deploy existing Solidity smart contracts and DApp frontends to Moonbeam with minimal changes. As a parachain on the Polkadot network, Moonbeam benefits from the shared security of the Polkadot relay chain and integrations with other chains connected to Polkadot.

OriginTrail is a decentralized knowledge graph that enables the world's data assets to be structured, linked, persistent, and understandable. OriginTrail can organize, discover, and verify anything, from physical to digital assets, such as supply chain items, art, diplomas, certificates, NFTs, DeFi, and more.

CLV is a one-stop infrastructure platform for cross-chain and decentralized applications. The CLV Chain is a Substrate-based Layer 1 chain that is EVM-compatible and cross-chain interoperable. The CLV Wallet is a multi-chain, all-in-one wallet for day-to-day, DeFi, and gaming purposes.

Bifrost is a decentralized derivatives protocol that provides cross-chain liquidity for staked assets. It leverages Cross-Consensus Messaging (XCM) to offer cross-chain liquid staking services for multiple chains. The mission of Bifrost is to provide standardized cross-chain interest-bearing derivatives for Polkadot relay chains, parachains, and heterogeneous chains connected to Polkadot.

The Nodle Network is a decentralized, low-range wireless network that provides access to IoT devices. The Nodle Chain is the parachain that powers the Network. It is designed to offer a global, easy-to-use and decentralized communications network for IoT devices. The Nodle network stack is a software solution that monetizes hardware and IoT devices. With Nodle, Network Contributors share their communications resources to enable connectivity for the network. These Contributors become part of a shared, interoperable "Citizen Network," and are incentivized to scale the network through a Proof of Connectivity algorithm. This algorithm is based on the number of base stations, network bandwidth, and geographic coverage. The Nodle Network is deployed by adding software to wireless devices such as smartphones, routers, fixed base stations, drones, vehicles, and other connected devices. Through an economy of connectivity and decentralized infrastructure, the Nodle Network provides a low-cost, global and scalable connectivity solution, enabling many services to be built on top of the Network.

Acala is a decentralized finance network powering the aUSD ecosystem, designed to be the financial hub of the Polkadot ecosystem. It is a layer-1 smart contract platform that is scalable, Ethereum-compatible, and optimized for DeFi. With Acala EVM+, developers can leverage the aUSD ecosystem while benefiting from the best of Ethereum and the full power of Substrate.

EQ finance is a decentralized, interoperable money market. It aims to address the fragmentation issue of DeFi across multiple protocols and the lack of cross-chain interoperability. It combines a lending platform, a professional-grade cross-chain decentralized exchange, stablecoins, synthetic assets, margin trading, and perpetual swaps in a single, easy-to-use interface.

Polkadex is a fully decentralized, peer-to-peer orderbook-based cryptocurrency exchange for the DeFi ecosystem. It is built on Substrate and designed to become the ultimate trading engine for Web3.

Crust Network is a decentralized cloud storage provider designed to realize three core values: decentralization, privacy, and assurance. It supports multiple storage-layer protocols such as IPFS, and provides instant accessible on-chain storage functions to users. Crust's technical stack is also capable of supporting data manipulation and computing. Crust Network has three main functions: NFT and Metaverse Metadata storage, personal file storage, and Website/dApp hosting.

Mandala Chain is a Polkadot parachain that seamlessly integrates government and enterprise applications with the public and retail sectors. Mandala Chain’s first use case, IDCHAIN, is working with the regulatory entity for Indonesia’s top-level .id web domain.

Aventus Network is a layer-2 blockchain protocol that brings scalability, lower costs, and speed to Ethereum transactions. It is moving towards becoming a parachain on Polkadot. Originally, Aventus Network was an event ticketing platform based on blockchain.

Efinity, developed by Enjin, is a next-generation blockchain for digital assets built on Polkadot. It aims to facilitate the transactions of NFTs in all major industries.

Hydration is a next-gen DeFi protocol which is designed to bring an ocean of liquidity to Polkadot. Its tool for the job the Hydration Omnipool - an innovative Automated Market Maker (AMM) which unlocks unparalleled efficiencies by combining all assets in a single trading pool.

Bitgreen seeks to finance real-world assets and impactful projects related to conservation, clean energy, and social enterprise. Investors will be able to identify compelling projects, as well as syndications, and invest cryptocurrency, which thereafter mints fungible tokens from these issuances to be held or transacted on a native CEX.

OmniBTC is a decentralized cross-chain swap and lend & borrow platform, aiming to connect and unify all the on-chain liquidity. Supporting more than 14 chains and 20+DEX, it fully enables users to bridge any token on any chain with one click.

Integritee is a platform for developers to build decentralized applications that benefit from unparalleled speed, verifiable privacy, and interoperability at scale. Integrity offers a wide range of products and services based on blockchain technology, including a software development kit (SDK) for trusted off-chain workers, second-layer sidechains and oracles, as well as a decentralized attestation service for trusted execution environments (TEEs). Integrity enables developers to directly invoke hardware enclaves for trusted execution using a highly scalable, second-layer blockchain solution.

InvArch is a layer-1 blockchain designed to support and empower the future creator economy. It provides a new foundation through its powerful NFT primitives and DAO solutions.

Hashed Network enables the full business lifecycle for digitally-native organizations and web3-curious businesses seeking the benefits of decentralized digital economies. Hashed Network is committed to helping organizations unlock the business value of blockchain.

Bit.Country is a Metaverse-as-a-Service (MaaS) platform. Users can launch their own metaverse project in just 12 seconds. Each metaverse comes with an NFT Marketplace, Map Engine, Land Economy, NFT Facilities, and a Customizable 3D World Engine.

Unique Network is an infrastructure for the next generation of Non-Fungible Tokens (NFTs). It is the first NFT chain for Kusama and Polkadot, providing developers with independence from high network transaction fees, frequent upgrades, and siloed NFTs.

Watr is a public Layer 1 protocol and Polkadot parachain for dApps servicing provenance, procurement, financing, and trade in the $17 trillion dollar commodities industry – from carbon credits to metals, agriculture, and energy. The objective is to achieve interoperability across digital ventures servicing the end-to-end of a new class of ethical commodities for physical delivery. Watr is co-founded in a first-of-its-kind collaboration between industry giants, commodities, and Web 3 pioneers, including Parity Technologies.

KILT is a blockchain-based identity protocol for issuing self-sovereign, anonymous, verifiable credentials and decentralized identifiers.

Pendulum is an open-source blockchain that attempts to bridge the gap between fiat and DeFi ecosystems by creating a fiat-optimized smart contract blockchain. It is built on Substrate, allowing DeFi applications to connect to the foreign exchange market and build automated market makers (AMMs) to offer scalable liquidity pools for fiat currencies and yield earning opportunities for fiat token holders. With the goal of becoming a Polkadot parachain for maximum security and interoperability, Pendulum strives to bring the benefits of DeFi to the world of fiat.

Darwinia is a cross-chain messaging infrastructure that offers a reliable and programmable platform for decentralized applications. It provides developers with an SDK, allowing them to easily integrate cross-chain capabilities into their Dapps.

Coinversation Protocol is a DeFi protocol platform of the Polkadot ecology. It has been expanded from a synthetic asset protocol to a derivative ecosystem, including parachains, DEX, synthetic assets, and stablecoin protocols.