Avantis is an oracle-based synthetic derivatives protocol where users can trade crypto and real world assets with up to 100x leverage, and earn yield as a market-maker by providing USDC liquidity.

Felix is a synthetic dollar protocol on Hyperliquid L1 that allows users to deposit collateral and borrow feUSD to earn income using Felix vaults.

Synthetix is a decentralized platform for synthetic assets that provides on-chain exposure to real-world currencies, commodities, stocks, and indices. These synthetic assets (Synths) are backed by Synthetix Network Tokens (SNX) locked into a smart contract as collateral. The protocol also issued a stablecoin sUSD. Synths track the prices of various assets, allowing crypto-native and unbanked users to trade peer-to-contract (P2C) on Synthetix Exchange without liquidity restrictions.

Own Protocol is a permissionless synthetic stock issuance protocol. Users can mint synthetic stocks and LPs earn yield for backing these assets.

Ostium is a synthetic asset protocol that enables institutional and retail traders and hedgers to gain exposure to commodities on-chain.

Tapio is a synthetic asset protocol designed to optimize liquidity fragmentation by unifying different asset formats into a highly efficient and usable standard.

TWIN Finance is a decentralized finance protocol on blockchain for synthetic derivatives of real-world assets. Its twin-token mechanism enables synthetic asset creation, improves capital efficiency, and reduces price risks for liquidity providers.

Reflect is a Synthetic Currency Exchange Protocol on the Solana Network. Reflect Protocol uniquely enables Delta-Neutral money from Liquid Staking Tokens. Capturing both native yield and perpetual yields to provide a high yield dollarized product to anyone around the globe at instant latency.

Delpho is a synthetic dollar built on Hyperliquid and powered by perpetual contracts.

SYNTHR is a cross-chain liquidity protocol that supports a secure, zero-slip execution environment. It consists of a combination of pull and push oracles, a zero-slippage omnichain liquidity layer, and multiple independent consensus layers.

XSY is building a Next Gen Digital Synthetic Dollar, $UTY, creating a structured, scalable way to unlock blockchain ecosystems dormant potential.

Crafting Finance is a synthetic asset issuance protocol, decentralized contract trading exchange and NFT fragmentation platform based on the Near smart contract chain. Users can also convert minted assets into other assets through the trading platform, so as to realize the purpose of shorting the asset and longing other assets.

Citadel Labs is a decentralized fundraising platform that invests in philanthropy, patent tokens, and scientific research ventures.

Neutrl is a high-yield synthetic dollar, leveraging OTC arbitrage strategies across altcoin markets for scalable, market-neutral returns.

KALATA is the backbone for issuing and transacting Synthetic Assets, providing everyone with a seamless experience of real-world financial assets. Additionally, KALATA is a platform for trading derivatives and offering mortgages on decentralized Synthetic Assets.

Pharaoh Protocol is an extensive synthetic Protocol for Cosmos, allowing exposure to the prices of commodities, FOREX, and any crypto token with a price oracle feed.

PERI Finance is a decentralized, cross-chain synthetic issuance and derivative exchange protocol that provides unlimited liquidity on the Polkadot network. It gives users the opportunity to access a wide range of both traditional financial and crypto assets in the form of leveraged and non-leveraged synthetic products. We empower users with lower GAS fees, speedy transactions, and ample security from front-running or flash loan attacks.

Parity is a synthetic restaking protocol platform that generates more returns through synthetic yield and dynamic allocation.

OpenDelta is a delta-neutral, yield-bearing synthetic dollar powered by Bitcoin derivatives. OpenDelta’s flagship token, USDO, will retain its dollar value by hedging bitcoin (BTC) deposited by users as collateral.

Taiga is a synthetic asset protocol designed to unify different formats of staking and crowdloan derivatives into a highly efficient standard on Dotsama ecosystem. It is comprised of Stable Asset mechanism, as well the Stable Swap engine.

Porto is building Sui-native synthetic assets, starting with pUSD: the backbone of liquidity on Sui.

Duet is a multi-chain synthetic assets ecosystem, enabling pegged assets from various markets, including stocks, indexes, ETFs, and commodities, to be traded on Web3.

Perlin is a decentralized synthetic liquidity pool that supports the creation and trading of synthetic assets. In partnership with UMA, PerlinX users will be able to generate synthetic assets of any kind by over-collateralizing PERL. Perlin includes a cloud computing layer known as the PerlinX Network, which will serve as a marketplace for computing resources between vendors and customers.

Parasset is a next-generation, synthetic asset project incubated by NEST LABS.

Bao Finance is a cross-chain DeFi ecosystem that adds features to existing DeFi systems. It is building innovative products such as: - Synthetics that use LP tokens as collateral; - Lending pools which will use LP tokens as collateral; - An auto-balancer system that will manage a user's synthetics, futures and LP positions; - Options, perpetual futures, margin trading and limit orders using LP tokens as collateral.

Metronome is a complete synthetic protocol that enables users to generate a variety of synthetics using crypto assets as collateral.

Synthetify is a decentralized protocol for synthetic assets based on the Solana blockchain. It enables the creation and exchange of synthetic assets that closely track the prices of their real-world counterparts. The synthetic tokens are based on the SPL-Token standard, which allows them to be easily integrated with other DeFi applications such as AMMs.

Shadows is a decentralized synthetic asset issuance protocol built on Substrate. The value of these synthetic assets is underpinned by DOWS, and as long as DOWS is locked in a smart contract, synthetic assets can be issued. Shadows is a hub for issuing, trading, lending, and borrowing synthetic assets.

eBTC is a collateralized crypto asset soft pegged to the price of Bitcoin and built on the Ethereum network. It is backed exclusively by Lido's stETH and powered by immutable smart contracts with minimized counterparty reliance. It is designed to be the most decentralized synthetic Bitcoin in DeFi and offers the ability for anyone in the world to borrow BTC at no cost.

Indigo is a decentralized non-custodial synthetic assets protocol built for Cardano. Using smart contracts, Indigo allows users to create fully collateralized synthetic assets known within the protocol as iAssets.