LayerZero is an Omnichain Interoperability Protocol designed for lightweight message passing across chains. It provides authentic and guaranteed message delivery with configurable trustlessness, implemented as a set of gas-efficient, non-upgradable smart contracts.

Chainlink is an oracle infrastructure bringing the capital markets onchain and powering the majority of decentralized finance (DeFi). The Chainlink stack provides the essential data, interoperability, compliance, and privacy standards needed to power advanced blockchain use cases for institutional tokenized assets, lending, payments, stablecoins, and more.

Wormhole is a decentralized, universal message-passing protocol that enables developers and users of cross chain applications to leverage the advantages of multiple ecosystems.

Beyond is a native Bitcoin L1 interoperability protocol, providing the necessary infrastructure for users to securely bridge any token to, from, and within Bitcoin L1.

Openverse Global is a Layer0 hub network based on blockchain technology. It is based on the existing blockchain technology and proposes the concept of "fully open protocol cross-chain". It will realize "the transmission of value (token/NFT/message) between different blockchains, metaverses and the traditional Internet is as simple as sending email". Openverse has proposed protocol systems such as the "Bitcurrency VRC10 Protocol", "Privcurrency VRC11 Protocol", and "Public Currency Issurance Mechanism, PCIM".

Portal is the custody-less interoperability protocol for Bitcoin. Portal enables fast, low cost atomic swaps between native Bitcoin assets like BTC, Ordinals, and Runes, to L2s and other L1s. With Portal’s technical breakthroughs, there is no bridging or wrapping.

Axelar is a decentralized cross-chain communication network, aiming to level-up interoperability in Web3 by connecting heterogeneous blockchains and enabling asset mobility and program composability in an optimized way for both builders and end-users. The two layers of Axelar are the network and the API above it. At the core of Axelar is a permissionless overlay network that provides Turing-complete cross-chain communication through proof-of-stake and permissionless protocols. On top of the network are APIs and protocols, an application-development layer that developers use to compose across any number of chains. Once integrated, all new interconnected blockchains become interoperable with the application, resulting in limitless network effects.

Quant is a cross-chain platform, and its main product, Overledger, is a DLT Gateway for businesses. Quant's platform is protocol-agnostic, simplifying and connecting any system to any network to any DLT anywhere in the world, allowing them to securely, simply and cost-effectively share, view, and exchange information and value.The Overledger Operating System from Quant Network automates trust functions between multiple blockchains. This system is designed to be a blockchain OS, with the goal of connecting blockchains and networks (such as those for financial services, healthcare, and more) on a global scale, while preserving interoperability.

Union is a yper-efficient interoperability protocol connects all blockchains and rollups, across any ecosystem. It's based on consensus verification and has no dependencies on trusted third parties, oracles, multi-signatures, or MPC.

TeleSwap is a trustless and universal interoperability protocol that provides developers with an infrastructure to build cross-chain applications. With it, users can transfer any data, such as messages, contract calls, tokens, or NFTs, between blockchains.

Hyperbridge is a cryptoeconomic coprocessor for secure, verifiable interoperability powered by consensus and storage proofs. Hyperbridge is the HTTPS of blockchain interoperability, providing developers with onchain and off-chain SDKs for securely sending cross-chain messages (POST requests) and reading on-chain storage (GET requests).

Universal is a wrapped asset protocol designed to enable any token to trade on any chain. Universal can enhance liquidity management, simplify token availability across multiple chains, and significantly improve the overall user experience in crypto ecosystems.

Everclear is the new foundation of the chain abstraction stack, integrating with intent protocols, solver networks, modular blockchains, and dApps to enable the most efficient transaction settlement at the best possible price. Everclear coordinates the global settlement of liquidity between chains, solving fragmentation for modular blockchains.

Stripchain is a cross-chain interoperability protocolallows developers to create commands called intents to perform actions like transferring data between blockchains. Based on a system called stripVM, it will enable applications to communicate and coordinate with different protocols.

Units Network is a modular blockchain ecosystem enabling users to launch EVM-compatible sidechains. It features L0 scalability, restaking for consensus, and DAO-based governance. UNIT0 tokens facilitate transactions, voting, and incentives for projects like CrossCurve and Unilend.

Holograph is an omnichain tokenization protocol, enabling asset issuers to mint natively composable omnichain tokens. Holograph works by burning tokens on the source chain, sending a message via a messaging protocol to the destination chain, and then reminting the same number of tokens to the same contract address. This unifies liquidity, eliminates slippage, and preserves fungibility across blockchains.

Newton is a chain unification network jointly launched by Magic Labs and Polygon Labs, with a single wallet and balance across the chain. Newton is designed to boost interoperability across Polygon’s AggLayer, which connects layer-1 and layer-2 chains with shared liquidity. The network includes a wallet that lets users store and transfer various digital assets across various blockchain platforms with “simplified” cross-chain swaps.

Butter Network is an Omnichain Interoperability Hub integrated with ZK technology that enables users with global DAPP accessibility and data availability, building an infrastructure that makes transactions transverse across chain to chain freely and securely.

oooo is a modular omnichain interoperability protocol supporting the Bitcoin ecosystem. Its modular communication protocol architecture ensures the integrity and reliability of data and transactions within the system. This approach resolves blockchain isolation and liquidity fragmentation, boosting capital efficiency and utilization, and ultimately improving the user experience. oooo is pioneering the next evolution in blockchain interoperability by introducing AI Omninet — an intelligent protocol that transforms cross-chain intents into seamless operations.

XRPL EVM Sidechain is a platform integrating Ethereum Virtual Machine with XRP Ledger. It supports Solidity smart contracts, uses XRP as the native token, and enables cross-chain transfers via Axelar bridge, built on Cosmos SDK with Proof of Authority consensus.

Rabbit Chain is an innovative blockchain project that integrates AI technology and is currently in the testing phase.

GVNR is a General Message Passing Protocol that enables seamless connection between every compatible chain, peer-to-peer. GVNR is built for all users and especially AI Agents. GVNR enables permissionless universal control of all chains and all assets. GVNR can be deployed to any permissionless or permissioned blockchain, and will be self-deployable by chains, foundations or enterprises that wish to access the widest possible liquidity.

ValenceZone is a cross-chain protocol enabling programmatic relationships between crypto-native organizations. Valence expands the scope of the IBC Protocol, enabling economic agreements such as adjusting treasury compositions according to market conditions or lending POL.

Diffuse is a zkServerless protocol dedicated to redefining trustless interoperability in Web3. By integrating decentralized and trustless principles with intuitive usability and cost-efficient scalability, it redefines the way protocols might communicate, effectively eliminating critical barriers such as slow proof generation, high verification costs, and complex infrastructure demands. zkServerless is an asynchronous computational layer for processing data from arbitrary origins, combining zero-knowledge proof technology with a serverless paradigm to enable trustless, automated, and scalable data processing and interactions without reliance on centralized infrastructure.

Counterfactual Network introduces an innovative framework for omni apps, enabling the deployment of genuine cross-chain decentralized applications within the Ethereum ecosystem. In Counterfactual Network, all supported L2s are abstracted into the Unified Execution Layer (UEL). This abstraction simplifies the network architecture, allowing for seamless interaction and execution across multiple L2 platforms.

Genitive Network is a FHE (Fully Homomorphic Encryption) based BTC L2 interoperability protocol. Genitive Network, distinct from multi-signature bridges, utilizes FHE for EVM contract deployment with privacy computational capabilities, enabling fully onchain privacy while aligning with the security levels of BTC mainnet.

Dante Network is a general middle layer protocol that enables interoperability among multiple chains and integrates diverse resources to empower dApps.

Soul Bridge is an interoperability protocol that enables cross-chain identity verification.

zkBTC is a ZKP-based cross-chain bridge that connects the Bitcoin and Ethereum ecosystem with seamless interoperability, offering Bitcoin holders a secure gateway to explore Ethereum's thriving ecosystem.

MetaEngine provides a platform for interoperability of assets across metaverses.